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psma 617  (MedChemExpress)


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    Structured Review

    MedChemExpress psma 617
    Psma 617, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 93/100, based on 23 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/psma 617/product/MedChemExpress
    Average 93 stars, based on 23 article reviews
    psma 617 - by Bioz Stars, 2026-06
    93/100 stars

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    Novartis 177 lu lu psma 617
    Head-to-head comparison between [ 161 Tb]Tb-PSMA-617 and [ <t>177</t> <t>Lu]Lu-PSMA-617,</t> including preclinical dosimetry results in patients with mCRPC. (A) Mean absorbed doses (Gy/GBq) accumulated to kidneys, liver, parotid glands and submandibular glands determined for [ 161 Tb]Tb-PSMA-617 and [ 177 Lu]Lu-PSMA-617 over all patients. (B) Absorbed doses in tumor lesions determined after application of [ 161 Tb]Tb-PSMA-617 and [ 177 Lu]Lu-PSMA-617, respectively. (C) Mean tumor lesion absorbed dose per patient, and (D) absorbed dose in each individual tumor lesion. Copyrights © 2024 IVYSPRING.
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    Head-to-head comparison between [ 161 Tb]Tb-PSMA-617 and [ 177 Lu]Lu-PSMA-617, including preclinical dosimetry results in patients with mCRPC. (A) Mean absorbed doses (Gy/GBq) accumulated to kidneys, liver, parotid glands and submandibular glands determined for [ 161 Tb]Tb-PSMA-617 and [ 177 Lu]Lu-PSMA-617 over all patients. (B) Absorbed doses in tumor lesions determined after application of [ 161 Tb]Tb-PSMA-617 and [ 177 Lu]Lu-PSMA-617, respectively. (C) Mean tumor lesion absorbed dose per patient, and (D) absorbed dose in each individual tumor lesion. Copyrights © 2024 IVYSPRING.

    Journal: Theranostics

    Article Title: Contemporary opportunities and potential of Auger electron-emitting theranostics

    doi: 10.7150/thno.124671

    Figure Lengend Snippet: Head-to-head comparison between [ 161 Tb]Tb-PSMA-617 and [ 177 Lu]Lu-PSMA-617, including preclinical dosimetry results in patients with mCRPC. (A) Mean absorbed doses (Gy/GBq) accumulated to kidneys, liver, parotid glands and submandibular glands determined for [ 161 Tb]Tb-PSMA-617 and [ 177 Lu]Lu-PSMA-617 over all patients. (B) Absorbed doses in tumor lesions determined after application of [ 161 Tb]Tb-PSMA-617 and [ 177 Lu]Lu-PSMA-617, respectively. (C) Mean tumor lesion absorbed dose per patient, and (D) absorbed dose in each individual tumor lesion. Copyrights © 2024 IVYSPRING.

    Article Snippet: The key point is regulatory milestones have accelerated clinical translation: [ 177 Lu]Lu-DOTATATE (Lutathera ® , Novartis) was approved by the U.S. Food and Drug Administration (FDA) on January 26, 2018, for somatostatin receptor-positive gastroenteropancreatic neuroendocrine tumors (GEP-NETs) , , [ 68 Ga]Ga-PSMA-11 (Locametz ® , Novartis) was approved on December 1, 2020, for prostate-specific membrane antigen (PSMA)-positive prostate cancer imaging , ; and [ 177 Lu]Lu-PSMA-617 (Pluvicto ® , Novartis) was approved on March 23, 2022, for PSMA-positive metastatic castration-resistant prostate cancer (mCRPC) , .

    Techniques: Comparison